7MDL

High-resolution crystal structure of human SepSecS-tRNASec complex

7MDL の概要

• エントリーDOI: 10.2210/pdb7mdl/pdb
• 分子名称: O-phosphoseryl-tRNA(Sec) selenium transferase, RNA (90-MER), (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, ... (5 entities in total)
• 機能のキーワード: selenocysteine synthesis, protein translation, plp-dependent enzyme, rna binding, transferase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 262375.13

構造登録者

Puppala, A.,French, R.L.,Simonovic, M. (登録日: 2021-04-05, 公開日: 2022-11-09, 最終更新日: 2023-10-25)

• 主引用文献: Puppala, A.K.,Castillo Suchkou, J.,French, R.L.,Kiernan, K.A.,Simonovic, M.; Structural basis for the tRNA-dependent activation of the terminal complex of selenocysteine synthesis in humans.; Nucleic Acids Res., 2023; PubMed: 36929010; DOI: 10.1093/nar/gkad182

実験手法

X-RAY DIFFRACTION (2.32 Å)