7MCR

Human Apex/Ref1 homodimer formed under oxidative condition

Summary for 7MCR

• Entry DOI: 10.2210/pdb7mcr/pdb
• Descriptor: DNA-(apurinic or apyrimidinic site) endonuclease, mitochondrial, MAGNESIUM ION (3 entities in total)
• Functional Keywords: human apex/ref1, dna binding protein, dnase i, metal ion binding
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 31272.96

Authors

Nam, Y.W.,Yang, S. (deposition date: 2021-04-02, release date: 2022-04-06, Last modification date: 2024-11-20)

• Primary citation: Nam, Y.W.,Khanjani, E.B.,Fong, S.,Chawla, S.,Rahighi, S.,Parang, K.,Zhang, M.,Yang, S.; The Development of Novel Apurinic/Aprymidinic Endonuclease/Redox-factor 1 Inhibitors for the Treatment of Human Melanoma; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)