7MCA

Structure of the S. cerevisiae origin recognition complex bound to the replication initiator Cdc6 and the ARS1 origin DNA.

Summary for 7MCA

• Entry DOI: 10.2210/pdb7mca/pdb
• EMDB information: 23755 23818
• Descriptor: Origin recognition complex subunit 1, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... (11 entities in total)
• Functional Keywords: replication initiation, replication
• Biological source: Saccharomyces cerevisiae (Baker's yeast); More
• Total number of polymer chains: 9
• Total formula weight: 527256.28

Authors

Feng, X.,Li, H. (deposition date: 2021-04-01, release date: 2021-06-02, Last modification date: 2021-08-04)

• Primary citation: Feng, X.,Noguchi, Y.,Barbon, M.,Stillman, B.,Speck, C.,Li, H.; The structure of ORC-Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6.; Nat Commun, 12:3883-3883, 2021; PubMed: 34162887; DOI: 10.1038/s41467-021-24199-1

Experimental method

ELECTRON MICROSCOPY (3.6 Å)