7MAV

SARS-CoV-2 Main Protease (Mpro) in Complex with Covalent Inhibitor dFFCit-yne

Summary for 7MAV

• Entry DOI: 10.2210/pdb7mav/pdb
• Related PRD ID: PRD_002472
• Descriptor: 3C-like proteinase, N-{3-[(prop-2-yn-1-yl)oxy]propanoyl}-D-phenylalanyl-N-[(3S)-6-(carbamoylamino)-2-oxohexan-3-yl]-L-phenylalaninamide (3 entities in total)
• Functional Keywords: sars-cov-2, covid-19, covid19 protease, protease inhibitor, covalent, covalent inhibitor, complex, hydrolase inhibitor complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
• Total number of polymer chains: 2
• Total formula weight: 68806.44

Authors

Lockbaum, G.J.,Schiffer, C.A. (deposition date: 2021-03-31, release date: 2022-10-12, Last modification date: 2024-10-16)

• Primary citation: Lockbaum, G.J.,Schiffer, C.A.; SARS-CoV-2 Main Protease (Mpro) in Complex with Covalent Inhibitor dFFCit-yne; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.91 Å)