7MAF

HIV-1 Protease (I84V) in Complex with PU2 (LR2-79)

Summary for 7MAF

• Entry DOI: 10.2210/pdb7maf/pdb
• Descriptor: Protease, SULFATE ION, diethyl ({4-[(2S,3R)-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl][(2S)-2-methylbutyl]amino}butyl]phenoxy}methyl)phosphonate, ... (4 entities in total)
• Functional Keywords: hiv, nl4-3 protease, drug resistance, protease inhibitor, complex, hydrolase inhibitor complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Human immunodeficiency virus 1 (HIV-1)
• Total number of polymer chains: 2
• Total formula weight: 22474.49

Authors

Lockbaum, G.J.,Schiffer, C.A. (deposition date: 2021-03-31, release date: 2022-04-27, Last modification date: 2023-10-18)

• Primary citation: Lockbaum, G.J.,Schiffer, C.A.; HIV-1 Protease (I84V) in Complex with PU2 (LR2-79); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.902 Å)