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7M9T

HIV-1 Protease WT (NL4-3) in Complex with NR02-73

Summary for 7M9T
Entry DOI10.2210/pdb7m9t/pdb
DescriptorProtease, SULFATE ION, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{[(1S)-1-hydroxy-2,3-dihydro-1H-indene-5-sulfonyl][(2S)-2-methylbutyl]amino}-1-phenylbutan-2-yl]carbamate, ... (4 entities in total)
Functional Keywordshiv, nl4-3 protease, drug resistance, protease inhibitor, complex, hydrolase inhibitor complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHuman immunodeficiency virus 1 (HIV-1)
Total number of polymer chains2
Total formula weight22650.66
Authors
Lockbaum, G.J.,Schiffer, C.A. (deposition date: 2021-03-31, release date: 2022-08-31, Last modification date: 2023-10-18)
Primary citationLockbaum, G.J.,Schiffer, C.A.
HIV-1 Protease WT (NL4-3) in Complex with NR02-73
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

222415

PDB entries from 2024-07-10

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