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7M9I

HIV-1 Protease (I84V) in Complex with LR2-26

Summary for 7M9I
Entry DOI10.2210/pdb7m9i/pdb
DescriptorProtease, (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(2S,3R)-4-[({4-[(1R)-1,2-dihydroxyethyl]phenyl}sulfonyl)(2-ethylbutyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate, SULFATE ION, ... (4 entities in total)
Functional Keywordshiv, nl4-3 protease, drug resistance, protease inhibitor, complex, hydrolase inhibitor complex, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHuman immunodeficiency virus 1 (HIV-1)
Total number of polymer chains2
Total formula weight22640.62
Authors
Lockbaum, G.J.,Schiffer, C.A. (deposition date: 2021-03-31, release date: 2022-04-27, Last modification date: 2023-10-18)
Primary citationLockbaum, G.J.,Schiffer, C.A.
HIV-1 Protease (I84V) in Complex with LR2-26
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.817 Å)
Structure validation

221716

PDB entries from 2024-06-26

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