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7M77

NMR Structure of Schistocin-3 antimicrobial peptide in presence of DPC-d38 micelles

Summary for 7M77
Entry DOI10.2210/pdb7m77/pdb
Related7M67 7M73
NMR InformationBMRB: 30893
DescriptorSchistocin-3 antimicrobial peptide (1 entity in total)
Functional Keywordsantimicrobial peptide, antimicrobial protein
Biological sourceSchistosoma bovis
Total number of polymer chains1
Total formula weight1460.74
Authors
Santos, B.P.O.,de Magalhaes, M.T.Q. (deposition date: 2021-03-26, release date: 2021-09-15, Last modification date: 2024-11-13)
Primary citationSantos, B.P.O.,Alves, E.S.F.,Ferreira, C.S.,Ferreira-Silva, A.,Goes-Neto, A.,Verly, R.M.,Liao, L.M.,Oliveira, S.C.,de Magalhaes, M.T.Q.
Schistocins: Novel antimicrobial peptides encrypted in the Schistosoma mansoni Kunitz Inhibitor SmKI-1.
Biochim Biophys Acta Gen Subj, 1865:129989-129989, 2021
Cited by
PubMed Abstract: Here we describe a new class of cryptides (peptides encrypted within a larger protein) with antimicrobial properties, named schistocins, derived from SmKI-1, a key protein in Shistosoma mansoni survival. This is a multi-functional protein with biotechnological potential usage as a therapeutic molecule in inflammatory diseases and to control schistosomiasis.
PubMed: 34389467
DOI: 10.1016/j.bbagen.2021.129989
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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