7M67
NMR Structure of Schistocin-1 antimicrobial peptide in presence of DPC-d38 micelles
Summary for 7M67
| Entry DOI | 10.2210/pdb7m67/pdb |
| NMR Information | BMRB: 30891 |
| Descriptor | Schistocin-1 antimicrobial peptide (1 entity in total) |
| Functional Keywords | antimicrobial peptide, antimicrobial protein |
| Biological source | Schistosoma mansoni (Blood fluke) |
| Total number of polymer chains | 1 |
| Total formula weight | 2276.78 |
| Authors | Santos, B.P.O.,De Magalhaes, M.T.Q. (deposition date: 2021-03-25, release date: 2021-09-15, Last modification date: 2024-11-20) |
| Primary citation | Santos, B.P.O.,Alves, E.S.F.,Ferreira, C.S.,Ferreira-Silva, A.,Goes-Neto, A.,Verly, R.M.,Liao, L.M.,Oliveira, S.C.,de Magalhaes, M.T.Q. Schistocins: Novel antimicrobial peptides encrypted in the Schistosoma mansoni Kunitz Inhibitor SmKI-1. Biochim Biophys Acta Gen Subj, 1865:129989-129989, 2021 Cited by PubMed Abstract: Here we describe a new class of cryptides (peptides encrypted within a larger protein) with antimicrobial properties, named schistocins, derived from SmKI-1, a key protein in Shistosoma mansoni survival. This is a multi-functional protein with biotechnological potential usage as a therapeutic molecule in inflammatory diseases and to control schistosomiasis. PubMed: 34389467DOI: 10.1016/j.bbagen.2021.129989 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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