7M56

Structure of human endothelial nitric oxide synthase heme domain in complex with 7-((3-(3-aminophenethyl)phenoxy)methyl)quinolin-2-amine

7M56 の概要

• エントリーDOI: 10.2210/pdb7m56/pdb
• 分子名称: Nitric oxide synthase, endothelial, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (10 entities in total)
• 機能のキーワード: nitric oxide synthase inhibitor heme enzymes, oxidoreductase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 102520.81

構造登録者

Li, H.,Poulos, T.L. (登録日: 2021-03-22, 公開日: 2022-03-30, 最終更新日: 2023-10-18)

• 主引用文献: Lewis, M.C.,Weerawarnab, P.M.,Li, H.,Silverman, R.B.,Poulos, T.L.; Inhibition of bacterial nitric oxide synthase as an antimicrobial tool in fighting some antibiotic-resistant pathogens; To be published,

実験手法

X-RAY DIFFRACTION (1.957 Å)