7M40

Discovery of small molecule antagonists of human Retinoblastoma Binding Protein 4 (RBBP4)

7M40 の概要

• エントリーDOI: 10.2210/pdb7m40/pdb
• 分子名称: Histone-binding protein RBBP4, N~3~-{4-[3-(dimethylamino)pyrrolidin-1-yl]-6,7-dimethoxyquinazolin-2-yl}-N~1~,N~1~-dimethylpropane-1,3-diamine (3 entities in total)
• 機能のキーワード: rbbp4, structural genomics, structural genomics consortium, sgc, gene regulation
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 100624.84

構造登録者

Perveen, S.,Dong, A.,Tempel, W.,Zepeda-Velazquez, C.,Abbey, M.,McLeod, D.,Marcellus, R.,Mohammed, M.,Ensan, D.,Panagopoulos, D.,Trush, V.,Gibson, E.,Brown, P.J.,Arrowsmith, C.H.,Schapira, M.,Al-awar, R.,Vedadi, M.,Structural Genomics Consortium (SGC) (登録日: 2021-03-19, 公開日: 2021-05-12, 最終更新日: 2023-10-18)

• 主引用文献: Perveen, S.,Zepeda-Velazquez, C.,Abbey, M.,McLeod, D.,Marcellus, R.,Mohammed, M.,Ensan, D.,Panagopoulos, D.,Trush, V.,Gibson, E.,Tempel, W.,Brown, P.J.,Arrowsmith, C.H.,Schapira, M.,Al-awar, R.,Vedadi, M.,Structural Genomics Consortium (SGC); Discovery of small molecule antagonists of human Retinoblastoma Binding Protein 4 (RBBP4); To Be Published,

実験手法

X-RAY DIFFRACTION (1.88 Å)