7M32

Dihydropyrimidine Dehydrogenase (DPD) C671A Mutant Soaked with Uracil and NADPH Anaerobically

7M32 の概要

• エントリーDOI: 10.2210/pdb7m32/pdb
• 分子名称: Dihydropyrimidine dehydrogenase [NADP(+)], IRON/SULFUR CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... (9 entities in total)
• 機能のキーワード: dihydropyrimidine dehydrogenase, dpd, mutant, uracil, flavin, soaking, ligand, fmn, fad, flavoprotein, oxidoreductase
• 由来する生物種: Sus scrofa (Pig)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 457891.01

構造登録者

Butrin, A.,Beaupre, B.,Forouzesh, D.,Liu, D.,Moran, G. (登録日: 2021-03-18, 公開日: 2021-06-09, 最終更新日: 2023-10-18)

• 主引用文献: Beaupre, B.A.,Forouzesh, D.C.,Butrin, A.,Liu, D.,Moran, G.R.; Perturbing the Movement of Hydrogens to Delineate and Assign Events in the Reductive Activation and Turnover of Porcine Dihydropyrimidine Dehydrogenase.; Biochemistry, 60:1764-1775, 2021; PubMed: 34032117; DOI: 10.1021/acs.biochem.1c00243

実験手法

X-RAY DIFFRACTION (1.82 Å)