7LYX
Crystal structure of human CYP8B1 in complex with (S)-tioconazole
Summary for 7LYX
Entry DOI | 10.2210/pdb7lyx/pdb |
Descriptor | 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE, (S)-Tioconazole, ... (6 entities in total) |
Functional Keywords | oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 58265.13 |
Authors | Liu, J.,Scott, E.E. (deposition date: 2021-03-08, release date: 2022-08-17, Last modification date: 2023-10-25) |
Primary citation | Liu, J.,Carlson, H.A.,Scott, E.E. The structure and characterization of human cytochrome P450 8B1 supports future drug design for nonalcoholic fatty liver disease and diabetes. J.Biol.Chem., 298:102344-102344, 2022 Cited by PubMed: 35944583DOI: 10.1016/j.jbc.2022.102344 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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