7LYW

Crystal structure of the HCMV pentamer-specific antibody 2-25

Summary for 7LYW

• Entry DOI: 10.2210/pdb7lyw/pdb
• Descriptor: 2-25 Fab Heavy Chain, 2-25 Fab Light Chain (3 entities in total)
• Functional Keywords: antibody, fab, hcmv pentamer, cytomegalovirus, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 143739.54

Authors

Wrapp, D.,Mishra, A.K.,McLellan, J.S. (deposition date: 2021-03-08, release date: 2021-08-11, Last modification date: 2023-10-18)

• Primary citation: Wrapp, D.,Ye, X.,Ku, Z.,Su, H.,Jones, H.G.,Wang, N.,Mishra, A.K.,Freed, D.C.,Li, F.,Tang, A.,Li, L.,Jaijyan, D.K.,Zhu, H.,Wang, D.,Fu, T.M.,Zhang, N.,An, Z.,McLellan, J.S.; Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.; Sci Adv, 8:eabm2546-eabm2546, 2022; PubMed: 35275718; DOI: 10.1126/sciadv.abm2546

Experimental method

X-RAY DIFFRACTION (2.51 Å)