7LY9
Cryo-EM structure of 2909 Fab in complex with 3BNC117 Fab and CAP256.wk34.c80 SOSIP.RnS2 N160K HIV-1 Env trimer
Summary for 7LY9
Entry DOI | 10.2210/pdb7ly9/pdb |
EMDB information | 23589 |
Descriptor | 2909 Light Chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
Functional Keywords | cap256, v1v2, v2-apex, sosip, vaccine, tys, viral protein-immune system complex, viral protein/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 14 |
Total formula weight | 422724.33 |
Authors | Gorman, J.,Kwong, P.D. (deposition date: 2021-03-06, release date: 2021-08-18, Last modification date: 2024-10-16) |
Primary citation | Lee, M.,Changela, A.,Gorman, J.,Rawi, R.,Bylund, T.,Chao, C.W.,Lin, B.C.,Louder, M.K.,Olia, A.S.,Zhang, B.,Doria-Rose, N.A.,Zolla-Pazner, S.,Shapiro, L.,Chuang, G.Y.,Kwong, P.D. Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces. Nat Commun, 12:6470-6470, 2021 Cited by PubMed: 34753907DOI: 10.1038/s41467-021-26579-z PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.91 Å) |
Structure validation
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