7LWB

Crystal Structure of phospho-Rab8a with the RH2 domain (117-165) of RILPL2

Summary for 7LWB

• Entry DOI: 10.2210/pdb7lwb/pdb
• Descriptor: Ras-related protein Rab-8A, RILP-like protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: membrane trafficking, rab8a, effector, rab-interacting lysosomal protein-like 2, macromolecular complex, lrrk2 kinase, switch 2, phosphorylation ciliogenesis, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 27825.71

Authors

Waschbusch, D.,Khan, A.R. (deposition date: 2021-02-28, release date: 2021-03-10, Last modification date: 2023-10-18)

• Primary citation: Waschbusch, D.,Purlyte, E.,Khan, A.R.; Dual arginine recognition of LRRK2 phosphorylated Rab GTPases.; Biophys.J., 120:1846-1855, 2021; PubMed: 33887226; DOI: 10.1016/j.bpj.2021.03.030

Experimental method

X-RAY DIFFRACTION (1.9 Å)