7LW4
Structure of SARS-CoV-2 nsp16/nsp10 complex in presence of S-adenosyl-L-homocysteine (SAH)
Summary for 7LW4
Entry DOI | 10.2210/pdb7lw4/pdb |
Descriptor | 2'-O-methyltransferase, Non-structural protein 10, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (8 entities in total) |
Functional Keywords | product complex, hydrolase |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
Total number of polymer chains | 2 |
Total formula weight | 49601.32 |
Authors | Gupta, Y.K.,Viswanathan, T.,Misra, A.,Qi, S. (deposition date: 2021-02-27, release date: 2021-05-05, Last modification date: 2023-10-18) |
Primary citation | Viswanathan, T.,Misra, A.,Chan, S.H.,Qi, S.,Dai, N.,Arya, S.,Martinez-Sobrido, L.,Gupta, Y.K. A metal ion orients SARS-CoV-2 mRNA to ensure accurate 2'-O methylation of its first nucleotide. Nat Commun, 12:3287-3287, 2021 Cited by PubMed: 34078893DOI: 10.1038/s41467-021-23594-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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