7LT6
Structure of Partial Beta-Hairpin LIR from FNIP2 Bound to GABARAP
Summary for 7LT6
Entry DOI | 10.2210/pdb7lt6/pdb |
Related | 7LSW |
Descriptor | Folliculin-interacting protein 2,Gamma-aminobutyric acid receptor-associated protein (2 entities in total) |
Functional Keywords | autophagy, atg8, lir, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 49000.79 |
Authors | Appleton, B.A. (deposition date: 2021-02-18, release date: 2021-10-13, Last modification date: 2023-10-18) |
Primary citation | Goodwin, J.M.,Walkup 4th, W.G.,Hooper, K.,Li, T.,Kishi-Itakura, C.,Ng, A.,Lehmberg, T.,Jha, A.,Kommineni, S.,Fletcher, K.,Garcia-Fortanet, J.,Fan, Y.,Tang, Q.,Wei, M.,Agrawal, A.,Budhe, S.R.,Rouduri, S.R.,Baird, D.,Saunders, J.,Kiselar, J.,Chance, M.R.,Ballabio, A.,Appleton, B.A.,Brumell, J.H.,Florey, O.,Murphy, L.O. GABARAP sequesters the FLCN-FNIP tumor suppressor complex to couple autophagy with lysosomal biogenesis. Sci Adv, 7:eabj2485-eabj2485, 2021 Cited by PubMed: 34597140DOI: 10.1126/sciadv.abj2485 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report