7LT4

The aminoacrylate form of the beta-K167T mutant Tryptophan Synthase at 1.80 Angstrom resolution in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site

Summary for 7LT4

• Entry DOI: 10.2210/pdb7lt4/pdb
• Related: 4HN4 4HPJ 4HPX 6D0V 6VNT 6X0C 7KA1 7KQ9 7KWV 7KYT 7L03 7L1H 7LGX
• Descriptor: Tryptophan synthase alpha chain, Tryptophan synthase beta chain, DIMETHYL SULFOXIDE, ... (10 entities in total)
• Functional Keywords: inhibitor, aminoacrylate form, tryptophan synthase, lyase
• Biological source: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); More
• Total number of polymer chains: 2
• Total formula weight: 74135.09

Authors

Hilario, E.,Dunn, M.F.,Mueller, L.J. (deposition date: 2021-02-18, release date: 2022-02-23, Last modification date: 2023-10-18)

• Primary citation: Hilario, E.,Dunn, M.F.,Mueller, L.J.; The aminoacrylate form of the beta-K167T mutant Tryptophan Synthase at 1.80 Angstrom resolution in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site; To be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)