7LT4
The aminoacrylate form of the beta-K167T mutant Tryptophan Synthase at 1.80 Angstrom resolution in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site
Summary for 7LT4
Entry DOI | 10.2210/pdb7lt4/pdb |
Related | 4HN4 4HPJ 4HPX 6D0V 6VNT 6X0C 7KA1 7KQ9 7KWV 7KYT 7L03 7L1H 7LGX |
Descriptor | Tryptophan synthase alpha chain, Tryptophan synthase beta chain, DIMETHYL SULFOXIDE, ... (10 entities in total) |
Functional Keywords | inhibitor, aminoacrylate form, tryptophan synthase, lyase |
Biological source | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) More |
Total number of polymer chains | 2 |
Total formula weight | 74135.09 |
Authors | Hilario, E.,Dunn, M.F.,Mueller, L.J. (deposition date: 2021-02-18, release date: 2022-02-23, Last modification date: 2023-10-18) |
Primary citation | Hilario, E.,Dunn, M.F.,Mueller, L.J. The aminoacrylate form of the beta-K167T mutant Tryptophan Synthase at 1.80 Angstrom resolution in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and cesium ion at the metal coordination site To be Published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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