7LRZ
Structure of the Human ALK GRD
Summary for 7LRZ
Entry DOI | 10.2210/pdb7lrz/pdb |
Descriptor | ALK tyrosine kinase receptor (2 entities in total) |
Functional Keywords | glycine rich domain, neuroblastoma, cancer, oncogene, signaling protein, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 31846.14 |
Authors | Stayrook, S.,Li, T.,Klein, D.E. (deposition date: 2021-02-17, release date: 2021-11-24, Last modification date: 2023-10-18) |
Primary citation | Li, T.,Stayrook, S.E.,Tsutsui, Y.,Zhang, J.,Wang, Y.,Li, H.,Proffitt, A.,Krimmer, S.G.,Ahmed, M.,Belliveau, O.,Walker, I.X.,Mudumbi, K.C.,Suzuki, Y.,Lax, I.,Alvarado, D.,Lemmon, M.A.,Schlessinger, J.,Klein, D.E. Structural basis for ligand reception by anaplastic lymphoma kinase. Nature, 600:148-152, 2021 Cited by PubMed: 34819665DOI: 10.1038/s41586-021-04141-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.91 Å) |
Structure validation
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