7LRQ

Crystal structure of human SFPQ/NONO heterodimer, conserved DBHS region

7LRQ の概要

• エントリーDOI: 10.2210/pdb7lrq/pdb
• 分子名称: Splicing factor, proline- and glutamine-rich, Non-POU domain-containing octamer-binding protein, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: dbhs protein, nuclear protein, nucleic acid binding, paraspeckle formation, rna binding protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 60159.50

構造登録者

Marshall, A.C.,Bond, C.S.,Mohnen, I. (登録日: 2021-02-17, 公開日: 2021-05-12, 最終更新日: 2023-10-25)

• 主引用文献: Lee, P.W.,Marshall, A.C.,Knott, G.J.,Kobelke, S.,Martelotto, L.,Cho, E.,McMillan, P.J.,Lee, M.,Bond, C.S.,Fox, A.H.; Paraspeckle subnuclear bodies depend on dynamic heterodimerisation of DBHS RNA-binding proteins via their structured domains.; J.Biol.Chem., 298:102563-102563, 2022; PubMed: 36209820; DOI: 10.1016/j.jbc.2022.102563

実験手法

X-RAY DIFFRACTION (2.3 Å)