7LOT
Human PPAR Gamma LBD in Complex with Tetrazole Compound N-{3-[(4-methylbenzyl)oxy]benzyl}-2H-tetrazol-5-amine.
Summary for 7LOT
Entry DOI | 10.2210/pdb7lot/pdb |
Descriptor | Peroxisome proliferator-activated receptor gamma, ~{N}-[[3-[(4-methylphenyl)methoxy]phenyl]methyl]-1~{H}-1,2,3,4-tetrazol-5-amine (3 entities in total) |
Functional Keywords | ppar gamma, complex, tetrazole, gene regulation |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 64060.40 |
Authors | de Paula, K.,Nascimento, A.S. (deposition date: 2021-02-10, release date: 2021-02-24, Last modification date: 2023-10-18) |
Primary citation | de Paula, K.,Santos, J.C.,Mafud, A.C.,Nascimento, A.S. Tetrazoles as PPAR gamma ligands: A structural and computational investigation. J.Mol.Graph.Model., 106:107932-107932, 2021 Cited by PubMed: 33946041DOI: 10.1016/j.jmgm.2021.107932 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.29 Å) |
Structure validation
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