7LHT
Structure of the LRRK2 dimer
Summary for 7LHT
Entry DOI | 10.2210/pdb7lht/pdb |
EMDB information | 23350 |
Descriptor | Leucine-rich repeat serine/threonine-protein kinase 2, GUANOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE (3 entities in total) |
Functional Keywords | parkinson's disease, microtubule, kinase, cryo-em, neuropeptide, transferase, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 574756.08 |
Authors | Myasnikov, A.,Zhu, H.,Hixson, P.,Xie, B.,Yu, K.,Pitre, A.,Peng, J.,Sun, J. (deposition date: 2021-01-26, release date: 2021-06-16, Last modification date: 2024-03-06) |
Primary citation | Myasnikov, A.,Zhu, H.,Hixson, P.,Xie, B.,Yu, K.,Pitre, A.,Peng, J.,Sun, J. Structural analysis of the full-length human LRRK2. Cell, 184:3519-, 2021 Cited by PubMed: 34107286DOI: 10.1016/j.cell.2021.05.004 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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