7LHT
Structure of the LRRK2 dimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Leucine-rich repeat serine/threonine-protein kinase 2 | polymer | 2527 | 286427.7 | 2 | UniProt (Q5S007) Pfam (PF13855) Pfam (PF08477) Pfam (PF16095) Pfam (PF00069) | Homo sapiens (Human) | Dardarin |
| 2 | C, E (A, B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 3 | D, F (A, B) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) |
Sequence modifications
A, B: 1 - 2527 (UniProt: Q5S007)
| PDB | External Database | Details |
|---|---|---|
| His 50 | Arg 50 | variant |
| Thr 1647 | Ser 1647 | variant |
| Thr 2397 | Met 2397 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 572855.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1900.8 | |
| All* | Total formula weight | 574756.1 |
