7LHF

Structure of full-length IP3R1 channel solubilized in LNMG & lipid in the apo-state

Summary for 7LHF

• Entry DOI: 10.2210/pdb7lhf/pdb
• EMDB information: 23338
• Descriptor: Inositol 1,4,5-trisphosphate receptor type 1, (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, ZINC ION (3 entities in total)
• Functional Keywords: calcium channel, lipids, membrane protein
• Biological source: Rattus norvegicus (Rat)
• Total number of polymer chains: 4
• Total formula weight: 1270075.33

Authors

Baker, M.R.,Fan, G.,Baker, M.L.,Serysheva, I.I. (deposition date: 2021-01-22, release date: 2021-06-02, Last modification date: 2024-03-06)

• Primary citation: Baker, M.R.,Fan, G.,Seryshev, A.B.,Agosto, M.A.,Baker, M.L.,Serysheva, I.I.; Cryo-EM structure of type 1 IP3R channel in a lipid bilayer; Commun Biol, 4:625-, 2021; DOI: 10.1038/s42003-021-02156-4

Experimental method

ELECTRON MICROSCOPY (2.96 Å)