7LGX
The aminoacrylate form of mutant beta-K167T Salmonella typhimurium Tryptophan Synthase in complex with with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, benzimidazole (BZI) at the enzyme beta site and cesium ion at the metal coordination site at 1.80 Angstrom resolution
Summary for 7LGX
Entry DOI | 10.2210/pdb7lgx/pdb |
Related | 4HPX 6X0C 7KXC 7KYT |
Descriptor | Tryptophan synthase alpha chain, CESIUM ION, Tryptophan synthase beta chain, ... (11 entities in total) |
Functional Keywords | inhibitor, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) More |
Total number of polymer chains | 2 |
Total formula weight | 73487.65 |
Authors | Hilario, E.,Dunn, M.F.,Mueller, L.J. (deposition date: 2021-01-21, release date: 2022-01-26, Last modification date: 2023-10-18) |
Primary citation | Hilario, E.,Dunn, M.F.,Mueller, L.J. The aminoacrylate form of mutant beta-K167T Salmonella typhimurium Tryptophan Synthase in complex with with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, benzimidazole (BZI) at the enzyme beta site and cesium ion at the metal coordination site at 1.80 Angstrom resolution. To be Published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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