7LGX

The aminoacrylate form of mutant beta-K167T Salmonella typhimurium Tryptophan Synthase in complex with with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, benzimidazole (BZI) at the enzyme beta site and cesium ion at the metal coordination site at 1.80 Angstrom resolution

Summary for 7LGX

• Entry DOI: 10.2210/pdb7lgx/pdb
• Related: 4HPX 6X0C 7KXC 7KYT
• Descriptor: Tryptophan synthase alpha chain, CESIUM ION, Tryptophan synthase beta chain, ... (11 entities in total)
• Functional Keywords: inhibitor, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• Biological source: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720); More
• Total number of polymer chains: 2
• Total formula weight: 73487.65

Authors

Hilario, E.,Dunn, M.F.,Mueller, L.J. (deposition date: 2021-01-21, release date: 2022-01-26, Last modification date: 2023-10-18)

• Primary citation: Hilario, E.,Dunn, M.F.,Mueller, L.J.; The aminoacrylate form of mutant beta-K167T Salmonella typhimurium Tryptophan Synthase in complex with with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, benzimidazole (BZI) at the enzyme beta site and cesium ion at the metal coordination site at 1.80 Angstrom resolution.; To be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)