7LBL

Structure of Human IgG1 Fc

7LBL の概要

• エントリーDOI: 10.2210/pdb7lbl/pdb
• 分子名称: Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: effector, igg, antibody, fc, signaling protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55682.39

構造登録者

Fields, J.K.,Sundberg, E.J. (登録日: 2021-01-08, 公開日: 2021-01-20, 最終更新日: 2023-10-18)

• 主引用文献: Fields, J.K.,Sundberg, E.J.; Silent Antibodies: Generation of Hyperglycosylated FCs to Ablate Effector Functions; To Be Published,

実験手法

X-RAY DIFFRACTION (2.13 Å)