7LBF
CryoEM structure of the HCMV Trimer gHgLgO in complex with human Platelet-derived growth factor receptor alpha and neutralizing fabs 13H11 and MSL-109
Summary for 7LBF
Entry DOI | 10.2210/pdb7lbf/pdb |
EMDB information | 23253 |
Descriptor | Envelope glycoprotein H, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
Functional Keywords | virus, receptor, complex, neutralizing antibody, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Human cytomegalovirus (strain Merlin) (HHV-5) More |
Total number of polymer chains | 8 |
Total formula weight | 349960.31 |
Authors | Kschonsak, M.,Rouge, L.,Arthur, C.P.,Hoangdung, H.,Patel, N.,Kim, I.,Johnson, M.,Kraft, E.,Rohou, A.L.,Gill, A.,Martinez-Martin, N.,Payandeh, J.,Ciferri, C. (deposition date: 2021-01-07, release date: 2021-03-10, Last modification date: 2021-03-17) |
Primary citation | Kschonsak, M.,Rouge, L.,Arthur, C.P.,Hoangdung, H.,Patel, N.,Kim, I.,Johnson, M.C.,Kraft, E.,Rohou, A.L.,Gill, A.,Martinez-Martin, N.,Payandeh, J.,Ciferri, C. Structures of HCMV Trimer reveal the basis for receptor recognition and cell entry. Cell, 184:1232-, 2021 Cited by PubMed: 33626330DOI: 10.1016/j.cell.2021.01.036 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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