7LB0

Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-295

Summary for 7LB0

• Entry DOI: 10.2210/pdb7lb0/pdb
• Descriptor: Transcription initiation factor TFIID subunit 1, 1-{6-[(3R)-3-methylmorpholin-4-yl]-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl}cyclopropane-1-sulfonamide, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: bromodomain, taf1, tbp, transcription, general transcription factor iid, tfiid, tf250, non-bet, atr, kinase, gene regulation
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 31444.81

Authors

Karim, M.R.,Schonbrunn, E. (deposition date: 2021-01-07, release date: 2021-07-14, Last modification date: 2023-10-18)

• Primary citation: Karim, M.R.,Schonbrunn, E.; Crystal structure of the tandem bromodomain (BD1, BD2) of human TAF1 bound to ZS1-295; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.33 Å)