7L9T

Crystal Structure of Dihydrofolate reductase from Mycolicibacterium smegmatis in complex with SDDC-0001565 inhibitor

7L9T の概要

• エントリーDOI: 10.2210/pdb7l9t/pdb
• 分子名称: Dihydrofolate reductase, 3-(3-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: ssgcid, dihydrofolate reductase, sddc-0001565, structural genomics, seattle structural genomics center for infectious disease, oxidoreductase
• 由来する生物種: Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 19103.59

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2021-01-05, 公開日: 2021-01-20, 最終更新日: 2023-10-18)

• 主引用文献: DeBouver, N.D.,Bolejack, M.J.,Lorimer, D.D.,Horanyi, P.S.,Edwards, T.E.; Crystal Structure of Acetyl-coenzyme A synthetase synthetase from Coccidioides immitis in complex with PRX; to be published,

実験手法

X-RAY DIFFRACTION (1.8 Å)