7L9H

Crystal structure of human ARH3-D77A bound to magnesium and ADP-ribose

7L9H の概要

• エントリーDOI: 10.2210/pdb7l9h/pdb
• 分子名称: ADP-ribose glycohydrolase ARH3, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: adp-ribose, magnesium, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 159270.28

構造登録者

Pourfarjam, Y.,Kurinov, I.,Moss, J.,Kim, I.K. (登録日: 2021-01-04, 公開日: 2021-04-28, 最終更新日: 2023-10-18)

• 主引用文献: Pourfarjam, Y.,Ma, Z.,Kurinov, I.,Moss, J.,Kim, I.K.; Structural and biochemical analysis of human ADP-ribosyl-acceptor hydrolase 3 reveals the basis of metal selectivity and different roles for the two magnesium ions.; J.Biol.Chem., 296:100692-100692, 2021; PubMed: 33894202; DOI: 10.1016/j.jbc.2021.100692

実験手法

X-RAY DIFFRACTION (1.85 Å)