7L9E

Crystal structure of apo-alpha glucosidase

7L9E の概要

• エントリーDOI: 10.2210/pdb7l9e/pdb
• 分子名称: Neutral alpha-glucosidase AB Trypsin-cleaved Fragment #1, Neutral alpha-glucosidase AB Trypsin-cleaved Fragment #2, Neutral alpha-glucosidase AB Trypsin-cleaved Fragment #3, ... (10 entities in total)
• 機能のキーワード: alpha glucosidase ii, endoplasmic reticulum, hydrolase, inhibitor complex
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 235888.54

構造登録者

Karade, S.S.,Mariuzza, R.A. (登録日: 2021-01-03, 公開日: 2021-12-29, 最終更新日: 2023-10-18)

• 主引用文献: Karade, S.S.,Hill, M.L.,Kiappes, J.L.,Manne, R.,Aakula, B.,Zitzmann, N.,Warfield, K.L.,Treston, A.M.,Mariuzza, R.A.; N-Substituted Valiolamine Derivatives as Potent Inhibitors of Endoplasmic Reticulum alpha-Glucosidases I and II with Antiviral Activity.; J.Med.Chem., 64:18010-18024, 2021; PubMed: 34870992; DOI: 10.1021/acs.jmedchem.1c01377

実験手法

X-RAY DIFFRACTION (2.29 Å)