7L7R

CCHFV Gc prefusion monomer bound to ADI-36121 and ADI-37801 Fabs

Summary for 7L7R

• Entry DOI: 10.2210/pdb7l7r/pdb
• Descriptor: ADI-36121 Fab light chain, ADI-36121 Fab heavy chain, ADI-37801 Fab light chain, ... (7 entities in total)
• Functional Keywords: fusion protein, antibody, fab complex, class ii fusion, viral protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 5
• Total formula weight: 158077.45

Authors

Mishra, A.K.,McLellan, J.S. (deposition date: 2020-12-30, release date: 2021-12-01, Last modification date: 2023-10-18)

• Primary citation: Mishra, A.K.,Hellert, J.,Freitas, N.,Guardado-Calvo, P.,Haouz, A.,Fels, J.M.,Maurer, D.P.,Abelson, D.M.,Bornholdt, Z.A.,Walker, L.M.,Chandran, K.,Cosset, F.L.,McLellan, J.S.,Rey, F.A.; Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.; Science, 375:104-109, 2022; PubMed: 34793197; DOI: 10.1126/science.abl6502

Experimental method

X-RAY DIFFRACTION (2.1 Å)