7L7R
CCHFV Gc prefusion monomer bound to ADI-36121 and ADI-37801 Fabs
Summary for 7L7R
Entry DOI | 10.2210/pdb7l7r/pdb |
Descriptor | ADI-36121 Fab light chain, ADI-36121 Fab heavy chain, ADI-37801 Fab light chain, ... (7 entities in total) |
Functional Keywords | fusion protein, antibody, fab complex, class ii fusion, viral protein |
Biological source | Homo sapiens More |
Total number of polymer chains | 5 |
Total formula weight | 158077.45 |
Authors | Mishra, A.K.,McLellan, J.S. (deposition date: 2020-12-30, release date: 2021-12-01, Last modification date: 2023-10-18) |
Primary citation | Mishra, A.K.,Hellert, J.,Freitas, N.,Guardado-Calvo, P.,Haouz, A.,Fels, J.M.,Maurer, D.P.,Abelson, D.M.,Bornholdt, Z.A.,Walker, L.M.,Chandran, K.,Cosset, F.L.,McLellan, J.S.,Rey, F.A. Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies. Science, 375:104-109, 2022 Cited by PubMed: 34793197DOI: 10.1126/science.abl6502 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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