7L7R

CCHFV Gc prefusion monomer bound to ADI-36121 and ADI-37801 Fabs

7L7R の概要

• エントリーDOI: 10.2210/pdb7l7r/pdb
• 分子名称: ADI-36121 Fab light chain, ADI-36121 Fab heavy chain, ADI-37801 Fab light chain, ... (7 entities in total)
• 機能のキーワード: fusion protein, antibody, fab complex, class ii fusion, viral protein
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 158077.45

構造登録者

Mishra, A.K.,McLellan, J.S. (登録日: 2020-12-30, 公開日: 2021-12-01, 最終更新日: 2023-10-18)

• 主引用文献: Mishra, A.K.,Hellert, J.,Freitas, N.,Guardado-Calvo, P.,Haouz, A.,Fels, J.M.,Maurer, D.P.,Abelson, D.M.,Bornholdt, Z.A.,Walker, L.M.,Chandran, K.,Cosset, F.L.,McLellan, J.S.,Rey, F.A.; Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies.; Science, 375:104-109, 2022; PubMed: 34793197; DOI: 10.1126/science.abl6502

実験手法

X-RAY DIFFRACTION (2.1 Å)