7L6C
Crystal Structure of Enoyl-[acyl-carrier-protein] reductase InhA from Mycobacterium abscessus in complex with NAD
Summary for 7L6C
Entry DOI | 10.2210/pdb7l6c/pdb |
Related | 7KLI |
Descriptor | Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | ssgcid, enoyl-[acyl-carrier-protein] reductase, inha, mab_2722c, nad, structural genomics, seattle structural genomics center for infectious disease, oxidoreductase |
Biological source | Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543) |
Total number of polymer chains | 4 |
Total formula weight | 121650.09 |
Authors | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2020-12-23, release date: 2021-01-13, Last modification date: 2023-10-18) |
Primary citation | Alcaraz, M.,Roquet-Baneres, F.,Leon-Icaza, S.A.,Abendroth, J.,Boudehen, Y.M.,Cougoule, C.,Edwards, T.E.,Kremer, L. Efficacy and Mode of Action of a Direct Inhibitor of Mycobacterium abscessus InhA. Acs Infect Dis., 8:2171-2186, 2022 Cited by PubMed: 36107992DOI: 10.1021/acsinfecdis.2c00314 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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