7L6C

Crystal Structure of Enoyl-[acyl-carrier-protein] reductase InhA from Mycobacterium abscessus in complex with NAD

7L6C の概要

• エントリーDOI: 10.2210/pdb7l6c/pdb
• 関連するPDBエントリー: 7KLI
• 分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: ssgcid, enoyl-[acyl-carrier-protein] reductase, inha, mab_2722c, nad, structural genomics, seattle structural genomics center for infectious disease, oxidoreductase
• 由来する生物種: Mycobacteroides abscessus (strain ATCC 19977 / DSM 44196 / CIP 104536 / JCM 13569 / NCTC 13031 / TMC 1543)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 121650.09

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2020-12-23, 公開日: 2021-01-13, 最終更新日: 2023-10-18)

• 主引用文献: Alcaraz, M.,Roquet-Baneres, F.,Leon-Icaza, S.A.,Abendroth, J.,Boudehen, Y.M.,Cougoule, C.,Edwards, T.E.,Kremer, L.; Efficacy and Mode of Action of a Direct Inhibitor of Mycobacterium abscessus InhA.; Acs Infect Dis., 8:2171-2186, 2022; PubMed: 36107992; DOI: 10.1021/acsinfecdis.2c00314

実験手法

X-RAY DIFFRACTION (1.85 Å)