7L1T
Crystal structure of human holo SepSecS
Summary for 7L1T
Entry DOI | 10.2210/pdb7l1t/pdb |
Descriptor | O-phosphoseryl-tRNA(Sec) selenium transferase, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | selenocysteine synthesis, protein translation, plp-dependent enzyme, rna binding, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 58300.69 |
Authors | Puppala, A.,Castillo Suchkou, J.,Simonovic, M. (deposition date: 2020-12-15, release date: 2022-02-09, Last modification date: 2023-10-25) |
Primary citation | Puppala, A.K.,Castillo Suchkou, J.,French, R.L.,Kiernan, K.A.,Simonovic, M. Structural basis for the tRNA-dependent activation of the terminal complex of selenocysteine synthesis in humans. Nucleic Acids Res., 2023 Cited by PubMed: 36929010DOI: 10.1093/nar/gkad182 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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