7L1T

Crystal structure of human holo SepSecS

Summary for 7L1T

Entry DOI	10.2210/pdb7l1t/pdb
Descriptor	O-phosphoseryl-tRNA(Sec) selenium transferase, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	selenocysteine synthesis, protein translation, plp-dependent enzyme, rna binding, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	58300.69
Authors	Puppala, A.,Castillo Suchkou, J.,Simonovic, M. (deposition date: 2020-12-15, release date: 2022-02-09, Last modification date: 2023-10-25)
Primary citation	Puppala, A.K.,Castillo Suchkou, J.,French, R.L.,Kiernan, K.A.,Simonovic, M. Structural basis for the tRNA-dependent activation of the terminal complex of selenocysteine synthesis in humans. Nucleic Acids Res., 2023 Cited by PubMed: 36929010 DOI: 10.1093/nar/gkad182 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation