7L0L
Cryo-EM structure of the VRC316 clinical trial, vaccine-elicited, human antibody 316-310-1B11 in complex with an H2 CAN05 HA trimer
Summary for 7L0L
Entry DOI | 10.2210/pdb7l0l/pdb |
EMDB information | 23098 |
Descriptor | 316-310-1B11 Light Chain, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ... (5 entities in total) |
Functional Keywords | vrc, immune system, vrc316, h2, fab, flu, immune system-viral protein complex, immune system/viral protein |
Biological source | Homo sapiens More |
Total number of polymer chains | 12 |
Total formula weight | 341768.00 |
Authors | Gorman, J.,Kwong, P.D. (deposition date: 2020-12-11, release date: 2021-11-03, Last modification date: 2022-03-09) |
Primary citation | Andrews, S.F.,Raab, J.E.,Gorman, J.,Gillespie, R.A.,Cheung, C.S.F.,Rawi, R.,Cominsky, L.Y.,Boyington, J.C.,Creanga, A.,Shen, C.H.,Harris, D.R.,Olia, A.S.,Nazzari, A.F.,Zhou, T.,Houser, K.V.,Chen, G.L.,Mascola, J.R.,Graham, B.S.,Kanekiyo, M.,Ledgerwood, J.E.,Kwong, P.D.,McDermott, A.B. A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination. Nat Med, 28:373-382, 2022 Cited by PubMed: 35115707DOI: 10.1038/s41591-021-01636-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.85 Å) |
Structure validation
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