7L03

The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and sodium ion at the metal coordination site at 1.60 Angstrom resolution. Three water molecules are close to the amynoacrylate at the enzyme beta-site

7L03 の概要

• エントリーDOI: 10.2210/pdb7l03/pdb
• 関連するPDBエントリー: 4HN4 6D0V 6VNT 6X0C 7KA1 7KQ9 7KWV
• 分子名称: Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, ... (8 entities in total)
• 機能のキーワード: inhibitor, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Salmonella enterica subsp. enterica serovar Typhimurium; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72906.74

構造登録者

Hilario, E.,Dunn, M.F.,Mueller, L.J. (登録日: 2020-12-11, 公開日: 2021-12-22, 最終更新日: 2023-10-18)

• 主引用文献: Hilario, E.,Dunn, M.F.,Mueller, L.J.; The aminoacrylate form of the wild-type Salmonella typhimurium Tryptophan Synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site and sodium ion at the metal coordination site at 1.60 Angstrom resolution. Three water molecules are close to the amynoacrylate at the enzyme beta-site.; To be Published,

実験手法

X-RAY DIFFRACTION (1.6 Å)