7L00

Crystal Structure of C. difficile Enoyl-Acyl Carrier Protein Reductase (FabK) in Complex with an Inhibitor

Summary for 7L00

• Entry DOI: 10.2210/pdb7l00/pdb
• Descriptor: Enoyl-Acyl Carrier Protein Reductase FabK, FLAVIN MONONUCLEOTIDE, N-[6-(methylsulfonyl)-1,3-benzothiazol-2-yl]-2-[2-(1H-pyrrol-1-yl)-1,3-thiazol-4-yl]acetamide, ... (6 entities in total)
• Functional Keywords: enoyl acp reductase, inhibitor, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Clostridioides difficile
• Total number of polymer chains: 4
• Total formula weight: 136670.41

Authors

Akhtar, A.,Santarsiero, B.D.,Hevener, K.E. (deposition date: 2020-12-10, release date: 2021-12-22, Last modification date: 2023-10-18)

• Primary citation: Jones, J.A.,Hevener, K.E.,Alghanim, L.,Akhtar, A.,Santarsiero, B.D.; Crystal Structure of C. difficile Enoyl-Acyl Carrier Protein Reductase (FabK) in Complex with an Inhibitor; To be published,

Experimental method

X-RAY DIFFRACTION (1.72 Å)