7KZB
Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1antibodies
Summary for 7KZB
Entry DOI | 10.2210/pdb7kzb/pdb |
Descriptor | Fab heavy chain of CR3014-C8 antibody, Fab light chain of CR3014-C8 antibody, Spike glycoprotein, ... (8 entities in total) |
Functional Keywords | covid19, sars-cov2, antibody, antiviral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 5 |
Total formula weight | 119746.71 |
Authors | Langley, D.B.,Christ, D. (deposition date: 2020-12-10, release date: 2021-02-03, Last modification date: 2023-10-18) |
Primary citation | Rouet, R.,Mazigi, O.,Walker, G.J.,Langley, D.B.,Sobti, M.,Schofield, P.,Lenthall, H.,Jackson, J.,Ubiparipovic, S.,Henry, J.Y.,Abayasingam, A.,Burnett, D.,Kelleher, A.,Brink, R.,Bull, R.A.,Turville, S.,Stewart, A.G.,Goodnow, C.C.,Rawlinson, W.D.,Christ, D. Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies. Mabs, 13:1922134-1922134, Cited by PubMed: 34024246DOI: 10.1080/19420862.2021.1922134 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.83 Å) |
Structure validation
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