7KWY

X-ray Crystal Structure of PlyCB Mutant R66K

Summary for 7KWY

• Entry DOI: 10.2210/pdb7kwy/pdb
• Related: 7KWT 7KWW
• Descriptor: PlyCB, (4S)-2-METHYL-2,4-PENTANEDIOL (3 entities in total)
• Functional Keywords: endolysin, viral protein, phage effector protein, antimicrobial protein
• Biological source: Streptococcus virus C1
• Total number of polymer chains: 2
• Total formula weight: 15916.21

Authors

Williams, D.E.,Broendum, S.S.,Hayes, B.K.,Drinkwater, N.,McGowan, S. (deposition date: 2020-12-02, release date: 2021-04-07, Last modification date: 2023-10-18)

• Primary citation: Broendum, S.S.,Williams, D.E.,Hayes, B.K.,Kraus, F.,Fodor, J.,Clifton, B.E.,Geert Volbeda, A.,Codee, J.D.C.,Riley, B.T.,Drinkwater, N.,Farrow, K.A.,Tsyganov, K.,Heselpoth, R.D.,Nelson, D.C.,Jackson, C.J.,Buckle, A.M.,McGowan, S.; High avidity drives the interaction between the streptococcal C1 phage endolysin, PlyC, with the cell surface carbohydrates of Group A Streptococcus.; Mol.Microbiol., 116:397-415, 2021; PubMed: 33756056; DOI: 10.1111/mmi.14719

Experimental method

X-RAY DIFFRACTION (1.7 Å)