7KQX
MIF Y99C homotrimeric mutant
Summary for 7KQX
Entry DOI | 10.2210/pdb7kqx/pdb |
Descriptor | Macrophage migration inhibitory factor, SULFATE ION, GLYCEROL, ... (5 entities in total) |
Functional Keywords | mif, mutant, isomerase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 38855.15 |
Authors | Manjula, R.,Georgios, P.,Lolis, E.J. (deposition date: 2020-11-18, release date: 2022-01-19, Last modification date: 2023-10-25) |
Primary citation | Skeens, E.,Pantouris, G.,Shah, D.,Manjula, R.,Ombrello, M.J.,Maluf, N.K.,Bhandari, V.,Lisi, G.P.,Lolis, E.J. A Cysteine Variant at an Allosteric Site Alters MIF Dynamics and Biological Function in Homo- and Heterotrimeric Assemblies. Front Mol Biosci, 9:783669-783669, 2022 Cited by PubMed: 35252348DOI: 10.3389/fmolb.2022.783669 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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