7KQL
Anti-Tim3 antibody Fab complex
Summary for 7KQL
Entry DOI | 10.2210/pdb7kql/pdb |
Descriptor | Tim3.18 Fab heavy chain, Tim3.18 Fab light chain, Hepatitis A virus cellular receptor 2, ... (5 entities in total) |
Functional Keywords | tim3 havcr2 fab antibody, immune system |
Biological source | Homo sapiens More |
Total number of polymer chains | 3 |
Total formula weight | 63236.56 |
Authors | Deng, X.A.,West, S.M.,Strop, P. (deposition date: 2020-11-16, release date: 2022-02-09, Last modification date: 2023-10-18) |
Primary citation | Pagliano, O.,Morrison, R.M.,Chauvin, J.M.,Banerjee, H.,Davar, D.,Ding, Q.,Tanegashima, T.,Gao, W.,Chakka, S.R.,DeBlasio, R.,Lowin, A.,Kara, K.,Ka, M.,Zidi, B.,Amin, R.,Raphael, I.,Zhang, S.,Watkins, S.C.,Sander, C.,Kirkwood, J.M.,Bosenberg, M.,Anderson, A.C.,Kuchroo, V.K.,Kane, L.P.,Korman, A.J.,Rajpal, A.,West, S.M.,Han, M.,Bee, C.,Deng, X.,Schebye, X.M.,Strop, P.,Zarour, H.M. Tim-3 mediates T cell trogocytosis to limit antitumor immunity. J.Clin.Invest., 132:-, 2022 Cited by PubMed: 35316223DOI: 10.1172/JCI152864 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.49 Å) |
Structure validation
Download full validation report