7KQ7

Crystal structure of IL21R in complex with an antibody Fab fragment

7KQ7 の概要

• エントリーDOI: 10.2210/pdb7kq7/pdb
• 分子名称: Antibody heavy chain, Antibody light chain, Interleukin-21 receptor, ... (4 entities in total)
• 機能のキーワード: cytokine receptor, protein binding, protein binding-immune system complex, protein binding/immune system
• 由来する生物種: Rattus norvegicus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 72262.60

構造登録者

Mosyak, L.,Svenson, K. (登録日: 2020-11-13, 公開日: 2021-04-07, 最終更新日: 2024-04-03)

• 主引用文献: Campbell, S.M.,DeBartolo, J.,Apgar, J.R.,Mosyak, L.,McManus, V.,Beyer, S.,Bennett, E.M.,Lambert, M.,Cunningham, O.; Combining random mutagenesis, structure-guided design and next-generation sequencing to mitigate polyreactivity of an anti-IL-21R antibody.; Mabs, 13:1883239-1883239, 2021; PubMed: 33557673; DOI: 10.1080/19420862.2021.1883239

実験手法

X-RAY DIFFRACTION (2.203 Å)