7KP4

Crystal structure of human claudin-4 in complex with Clostridium perfringens enterotoxin C-terminal domain

Summary for 7KP4

Entry DOI	10.2210/pdb7kp4/pdb
Descriptor	Claudin-4, Heat-labile enterotoxin B chain (2 entities in total)
Functional Keywords	claudin, enterotoxin, tight junction protein, transmembrane protein, cell adhesion-toxin complex, cell adhesion/toxin
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	37728.80
Authors	Vecchio, A.J.,Stroud, R.M. (deposition date: 2020-11-10, release date: 2020-12-09, Last modification date: 2023-10-18)
Primary citation	Vecchio, A.J.,Rathnayake, S.S.,Stroud, R.M. Structural basis for Clostridium perfringens enterotoxin targeting of claudins at tight junctions in mammalian gut. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 33876770 DOI: 10.1073/pnas.2024651118 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.37 Å)

Structure validation